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The majority of breast malignancies are hormone responsive a
2019-04-17

The majority of breast malignancies are hormone responsive, and adjuvant endocrine therapy is used routinely to prevent breast cancer recurrence and death [6,7]. Tamoxifen was the past treatment of choice for endocrine-responsive postmenopausal breast cancer and was found to preserve BMD in postmeno
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br Over the past decade global concern about
2019-04-17

Over the past decade, global concern about the disproportionate burden of disease and mortality in low-income countries, especially in sub-Saharan Africa, has led to a substantial influx of funding for research by many donor and research agencies. This investment has energised in-country research;
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All patients with rickettsial infections reported by Dittric
2019-04-17

All patients with rickettsial infections reported by Dittrich and colleagues presented with fever at admission, and few patients presented with typical eschars of inoculation (only 3·6% of patients with murine typhus and 6·7% with scrub typhus). This finding might be a result of poor awareness about
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We present a case report of
2019-04-17

We present a case report of a patient with chronic myeloid leukemia (CML) who developed bilateral renal artery stenosis during tyrosine kinase inhibitor (TKI) therapy. Only a few reports associate TKIs with acute renal failure, and renovascular hypertension has not been previously described. Reports
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br Methods br Discussion We
2019-04-17

Methods Discussion We observed a significantly lower than expected Day +100 TRM. Other NMAT studies [4,5] have shown similar findings, although 60% of our trial pppa had high risk disease per the CIBMTR classification. In this and other studies, late TRM and disease progression remains proble
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In the days before Christmas adverse weather conditions and
2019-04-17

In the days before Christmas, 1952, adverse weather conditions and the burning of sulphurous coal led to the death of almost 12 000 people in London. Despite improvements in pollution prevention since the “Great Smog”, London continues to experience toxic air pollution linked to thousands of prematu
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br Possible reasons for the divergent results for the
2019-04-17

Possible reasons for the divergent results for the predictive value of PES for cardiac events First, there were methodological differences in the stimulation protocols used for PES, including the number of extrastimuli, the minimum coupling interval used (up to 200ms or refractoriness), the site
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Introduction Atrial fibrillation AF is the most common cardi
2019-04-17

Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice. The number of people with AF in the United States is currently estimated at 2.4 million, and the projected number with AF may exceed 10 million by 2050 [1,2]. Treatment for AF is also an im
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Y-27632 Therefore the patient was diagnosed with BIP
2019-04-17

Therefore, the patient was diagnosed with BIP, and steroid therapy with oral prednisolone at 40mg/day (0.5mg/kg/day) was initiated. The patient responded well to steroid therapy. After several weeks, his respiratory condition improved to Hugh–Jones class I. Since the imaging findings improved and th
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br Materials and methods Fifteen
2019-04-17

Materials and methods Fifteen healthy adult men participated in this study. The left anterior chest area was subdivided into 15 regions based on 5 longitudinal points (from the second to the sixth intercostal spaces) and 3 lateral points (including the left sternal border, midclavicular line, and
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More recently Brugada et al used flecainide to identify the
2019-04-17

More recently, Brugada et al. [131]. used flecainide to identify the full extent of low-voltage electrogram activity in the anterior RV and RVOT and targeted this region for RFA. In all 14 BrS patients, RFA eliminated abnormal bipolar electrograms, normalized ST-segment elevation on right precordial
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As countries and international platforms engage in post plan
2019-04-17

As countries and international platforms engage in post-2015 planning, now is the time to envision the ending of preventable maternal deaths, as stressed in a recent manifesto for maternal health. The global health faah inhibitors should build on past successes, and accelerate progress towards elim
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A recent meta analysis has
2019-04-16

A recent meta-analysis has shown that an enlarged LA increases the risk of AF recurrence after a single CPVI, regardless of the follow-up duration [5]. This finding can be applied to paroxysmal and persistent AF [6,7]. In clinical practice, measurement of LAD can provide a window into the status of
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De todas maneras no escapa a la tem tica
2019-04-16

De todas maneras no escapa a la temática de este trabajo la intuición de un contradictorio hecho: de que en este intento de interpretación de estos dos polémicos capítulos de Paradiso, dionisíacos, lo que estamos haciendo es, una vez más, buscar la sistematización iluminista, apolínea, a la que el m
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Of note gender equity might
2019-04-16

Of note, gender equity might continue despite the economic development of a society. Studies by Nussbaum and Sen have shown no direct relation between wealth and equity. Hence, some countries with high wealth, such as Saudi Arabia, also a have high degree of gender inequity, whereas others with low
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