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br Funding This work was supported by Department
2018-11-08

Funding This work was supported by Department of Neurosurgery, the University of Texas Health Science Center at Houston, Memorial Hermann Foundation-Staman Ogilvie Fund, the Bentsen Stroke Center, the TIRR Foundation through Mission Connect (No. 014-115), Craig H. Neilsen Foundation (No. 338617),
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br Experimental Procedures br Acknowledgments br
2018-11-08

Experimental Procedures Acknowledgments Introduction Hematopoietic stem ARRY-142886 (HSCs) are capable of both self-renewal and production of mature blood lineages. Players in this balanced regulation include transcription factors, cell-cycle regulators, signaling molecules, surface recept
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CSCs of breast tumors are commonly enriched by combinations
2018-11-08

CSCs of breast tumors are commonly enriched by combinations of several cell-surface antigens, such as CD44/CD24/EPCAM (Al-Hajj et al., 2003), or by high ALDH (aldehyde dehydrogenase) activity (Ginestier et al., 2007). However, existing markers lack specificity, also reflective of a substantial propo
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Several methods have been described to obtain neurons of spe
2018-11-08

Several methods have been described to obtain neurons of specific subtypes through differentiation of hPSCs, either via formation of three-dimensional (3D) embryoid bodies (EBs) or using monolayers as starting material (Amoroso et al., 2013; Boissart et al., 2013; Boulting et al., 2011; Eiraku and S
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These data are in agreement with prior studies
2018-11-08

These data are in agreement with prior studies demonstrating that hyaluronan levels play a critical role in determining the site of HSC lodgment/engraftment following transplantation (Avigdor et al., 2004; Ellis et al., 2007, 2009, 2011; Nilsson et al., 2003), and that HSC exhibit preferential engra
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The impairment of cardiac differentiation resulting from Cit
2018-11-07

The impairment of cardiac differentiation resulting from Cited2 depletion at the onset of ESC differentiation may be due to a consequent downregulation of Brachyury and Mesp1 expression. The decrease of Isl1, Nkx2.5, Gata4, and Tbx5 expression that we observed in Cited2-depleted cells at D5 of diffe
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Long run elasticity ln Long run semi elasticity The function
2018-11-07

Long-run elasticity: lnπ=1.06; Long-run semi-elasticity: π=0.29. The functional form given by (9) is not rejected, so that the money inelasticity buy betaxolol is rejected. Note also that the hypothesis of an elasticity equal to one (a1=1, Eq. (13)) could not be rejected. The value of the coeffici
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According to the tests of adequacy
2018-11-07

According to the tests of adequacy associated to unrestricted models in Table 5 we may not find further problems related to serial correlation as well as problems related to the validity of instruments. Again, SYS-GMM demonstrated being the preferable model given that the p-values of Diff-Sargan tes
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As already mentioned Rodrik provides an explanation
2018-11-07

As already mentioned, Rodrik (2006) provides an explanation called self-insurance protection against the capital outflows or changes in the exchange rate that may lead to a crisis. He also notes two types of costs involved in hoarding international reserves: (1) the spread between “the private secto
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It is unlikely that overexpression
2018-11-07

It is unlikely that overexpression of Ag85A and/or Ag85B was responsible for the VZV reactivations, as extensive pre-clinical and clinical use of these CB-5083 in other experimental TB vaccines has been completed without reports of zoster. Overexpression of the Rv3407 antigen has not been previously
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In the current issue of EBioMedicine describe the applicatio
2018-11-07

In the current issue of EBioMedicine, describe the application of a metabolomic platform based on bi-dimensional gas chromatography coupled to high-resolution mass spectrometry (GC×GC-TOF-MS) to identify biomarkers in serum samples that could associate with disease severity and predict the outcomes
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Reprogramming differentiated somatic cells to
2018-11-07

Reprogramming differentiated somatic apexbio dilution to induced pluripotent stem cells (iPSCs) enables re-differentiation to a wide array of cell types (Yamanaka, 2012) and is of considerable value for disease modeling, functional genomics, drug discovery, and regenerative medicine. The Next Gener
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Although these data indicate the potential effectiveness of
2018-11-07

Although these data indicate the potential effectiveness of passive immunotherapy by NAbs, the successful development of preventive HIV-1 vaccines requires a thorough understanding of how Nabs are induced during HIV-1 infection. The unusual maturation features of NAbs make them extremely difficult t
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br A manera de conclusiones El
2018-11-07

A manera de conclusiones El desequilibrio no ha podido subsanarse, debido gssg que la política monetaria no es capaz de alcanzar el declive sustancial de la tin, aun cuando su postura se haya mostrado “ultra-laxa”, y la permanencia de la tasa de interés neutral en niveles bajos viene a ser explic
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We then went on to
2018-11-07

We then went on to see if these proteins bound non-specifically to an cannabinoid receptor agonist of affinity resins; FLAG, TALON, Calmodulin and IgG and identified hundreds of non-specific interactors for each resin. We compared these lists to identify which proteins bind to multiple resins non-s
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