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El presente art culo se sustenta en informaci
2018-10-25

El presente artículo se sustenta en información tomada de los cinco periódicos que tuvieron mayor permanencia o duración durante la época en estudio, y que circularon semanalmente en Zacatecas entre 1917 y 1931, ICG001 saber: Revolución Social, El Heraldo, Opinión, Orientación y El Monitor Fresnille
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Although Indian banks have largely been able to adhere
2018-10-25

Although Indian banks have largely been able to adhere to guidelines of Reserve Bank of India for managing liquidity, factors affecting liquidity in Indian banks remain relatively unidentified owing to a scarcity of studies on management of liquidity in Indian banks (Bhati & De Zoysa, 2012). The re
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br Conflict of interest br Introduction Diabetes often
2018-10-25

Conflict of interest Introduction Diabetes, often referred as diabetes mellitus, describes a group of metabolic disorders characterized by common hyperglycaemia with disturbances of fat, carbohydrate and protein metabolism because of the defects in insulin releasing, insulin action, or both. A
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br Materials and methods br Acknowledgments We thank Dr Keis
2018-10-24

Materials and methods Acknowledgments We thank Dr. Keisuke Okita and Prof. Shinya Yamanaka for providing the reprogramming plasmids. Additionally, we would like to thank Tina Christoffersen and Birgit Kassow for skillful technical assistance. We acknowledge SHARE\'s Cross Faculty PhD Initiativ
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The NAD dependent protein silent information regulator Sir i
2018-10-24

The NAD-dependent protein silent information regulator 2 (Sir2) is a deacetylase for histones and other proteins and a key regulator of life span in several organisms. Sirtuin (SIRT)1 of the Sirtuin family is the closest homolog of yeast Sir2 in mammals and has critical functions in the regulation o
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br Experimental Procedures br Author Contributions br Acknow
2018-10-24

Experimental Procedures Author Contributions Acknowledgments Introduction Fragile X syndrome (FXS) affects approximately 1 in every 4,000 boys and 1 in 8,000 girls worldwide (Callan and Zarnescu, 2011; Penagarikano et al., 2007). It is now believed that FXS is the leading cause of inheri
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A common shortcoming of iHLCs and other iPSC derived
2018-10-24

A common shortcoming of iHLCs and other iPSC-derived neomycin sulfate lies in the fact that they often resemble a developmentally immature state compared to the fully differentiated adult counterpart (Engle and Puppala, 2013). In the field of iHLCs, current in vitro differentiation protocols result
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In Stevens and colleagues found penta snRNP
2018-10-24

In 2002, Stevens and colleagues found penta-snRNP, which contains all five spliceosomal snRNAs and over 60 pre-mRNA splicing factors, in yeast. They proposed that penta-snRNP associates prior to pre-mRNA substrate binding rather than with the pre-mRNA based on the results of a stepwise addition of d
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Our limited understanding of huSC biology can be attributed
2018-10-24

Our limited understanding of huSC biology can be attributed in part to the difficulty of obtaining tissue samples and of isolating a pure population of huSCs (Boldrin et al., 2010). By comparison, techniques for the prospective isolation of mouse SCs have identified a well-defined myogenic SC popula
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The pig has many advantages over
2018-10-24

The pig has many advantages over mouse models for pre-clinical studies involving hESC-CPC transplantation, namely its similar heart size and physiology to human. In addition, pig cardiomyocytes have been shown to exhibit similar contraction rates and analogous action potential duration to humans (St
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br Results br Discussion We established
2018-10-24

Results Discussion We established a method of 3D differentiation without feeder 2b3a inhibitors to generate hPSC-derived PAEC spheroids via isolated progenitor cells using CPM as a surface antigen, which is reportedly a biomarker of lung diseases, such as acute pneumonia and lung cancer (Drago
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Although the FDA considers analogous cell product data an
2018-10-24

Although the FDA considers analogous cell product data an acceptable option for preclinical studies, it requires substantial similarity between analogous animal and human products (FDA, 2013). Due to the significant differences in the innate and adaptive immune system (Mestas and Hughes, 2004), hema
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BTL-105 manufacturer BMSCs are potential stem cells with
2018-10-24

BMSCs are potential stem BTL-105 manufacturer with the ability to differentiate into osteoblasts or adipocytes depending on the situation (Pittenger et al., 1999). Indeed, several molecules possess a role in regulating the differentiation of BMSCs (D\'Alimonte et al., 2013; Shui et al., 2003; Yang e
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Introduction The correct functioning of the epigenome ensure
2018-10-24

Introduction The correct functioning of the epigenome ensures fidelity in the establishment of gene-expression programs that are compatible with specific cell identities. The need for tightly controlled epigenetic landscapes is of critical importance for stem cells, which are able to both self-rene
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Introduction The role of chromatin status
2018-10-24

Introduction The role of chromatin status on DNA damage response (DDR) and DNA double-strand break (DSB) repair has been extensively investigated in differentiated non-stem and cancer cells. Chromatin structure and remodeling plays an important role in the recruitment/assembly of repair factors and
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