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Introduction Myelodysplastic Syndrome MDS is a
2019-06-13
Introduction Myelodysplastic Syndrome (MDS) is a heterogeneous clonal disorder characterized by ineffective hematopoeisis and propensity for transformation into Acute Myelogenous Leukemia (AML). The Revised International Prognostic Scoring System (R-IPSS) is an accepted model used to predict overal
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SAR 405 Interpretation The SMART course can give orthopaedic
2019-06-13
Interpretation The SMART course can give orthopaedic surgeons practising in LMICs the skills and knowledge to successfully perform flaps and reduce amputation. While this SAR 405 course offers a collaborative, sustainable approach to reduce global surgery disparities in amputation, future investiga
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br Acknowledgments br Introduction Since
2019-06-13
Acknowledgments Introduction Since the first hospice was established in the United Kingdom in the late 1960s, the use of hospice and palliative care has become popular worldwide. In developed countries, hospice and palliative care are now used for services ranging from in-patient to community/
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Among our study patients without
2019-06-13
Among our study patients without supraventricular tachyarrhythmia, the prevalence of a spontaneous type 1 Brugada ECG and symptoms were higher and QRS duration was longer than in those with supraventricular tachyarrhythmia. Previous studies have revealed a spontaneous type 1 Brugada ECG and prolonge
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Only of ICD implantations are
2019-06-13
Only 1% of ICD implantations are performed in children. As a result, established methods of pediatric ICD implantation are lacking, and long-term outcomes are still unclear. Non-transvenous ICD systems are required in children [1,2], and we chose an epicardial system for our case. The advantage of t
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Repurposing use of approved drugs for new indications
2019-06-13
Repurposing (use of approved drugs for new indications) or repositioning (use of drugs whose development was not continued for new indications) of existing drugs has been put forward as a method to overcome some of these issues. Indeed, drug repositioning and repurposing could lead to higher rates o
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gpr120 agonist Pero adem s el ejemplo nos ilustra de c
2019-06-13
Pero, además, el ejemplo nos ilustra de cómo el sermón pastoral peruano no ahorra al indígena ninguno de los aspectos complejos del dogma. Pareciera que, en lo relativo gpr120 agonist este punto, no importara ya aquel requisito del decoro retórico sensibilizado hacia la capacidad de su receptor. Al
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ezh2 inhibitor br A manera de conclusi n
2019-06-13
A manera de conclusión El periódico La Lucha mantuvo una postura contra la intervención estadounidense en el proceso independentista cubano de 1895. Misma que refrendó en la coyuntura de la imposición de la Enmienda Platt. En esa ocasión utilizó un lenguaje grandilocuente que vislumbraba un futur
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br As mantenedoras e os mantidos S
2019-06-13
As mantenedoras e os mantidos São as organizações sociais que gerenciam os hospitais, determinam as políticas internas Pepstatin A serem seguidas, estipulam como devem ser os atendimentos dentro das normas contratuais e diretrizes dos sus, negociam os contratos de gestão e seus aditamentos, etc.
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Introduction By catalyzing post translational acetylation
2019-06-13
Introduction By catalyzing post-translational acetylation of lysine residues, the histone acetyl transferases (HAT) CREBBP and EP300 moderate the activities of both histone and non-histone proteins. This regulates vital cellular processes such as cell cycling and apoptosis by modulating chromatin s
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When the analysis was matching with
2019-06-12
When the analysis was matching with propensity score, OS was still significantly longer in JAK2+ patients (median not reached versus 73 months, p=.031) whereas JAK2 status had no significant prognostic value for OS in IPSS intermediate-2 and high patients (p=.18). Discussion In this series, whic
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actin inhibitor br Methods br Discussion We observed a
2019-06-12
Methods Discussion We observed a significantly lower than expected Day +100 TRM. Other NMAT studies [4,5] have shown similar findings, although 60% of our trial actin inhibitor had high risk disease per the CIBMTR classification. In this and other studies, late TRM and disease progression rema
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NCS is a rare syndrome In case series of NCS
2019-06-12
NCS is a rare syndrome. In case series of NCS 14–47% were associated with of lymphoproliferative disorders [reviewed in [12]]. Survival is usually dictated by the underlying disease and short in the setting of aggressive malignancies. Since NCS may be a manifestation of an underlying malignancy it h
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rgs protein br Comments The present two cases developed
2019-06-12
Comments The present two cases developed ACC during chemotherapy induced neutropenic for AML. ACC is a relatively rare complication in these patients’ population. It’s reported in 0.4% among all neutropenic episodes of patients with acute leukemia or aggressive lymphoma undergoing myelosuppressiv
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South Africa was the first
2019-06-12
South Africa was the first African country to implement the seven-valent pneumococcal conjugate vaccine (PCV7) in its routine infant immunisation programme (in 2009), with the novel schedule aligned to WHO\'s recommended Expanded Programme on Immunisation (EPI)—ie, a 2 + 1 schedule with doses at age
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