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The same jobs that have heavy
2018-10-24
The same jobs that have heavy physical work requirements may also have stressful psychosocial work conditions. Using national survey data from 27 European countries, Toch et al. (2014) examined the contribution of both physical and psychosocial work conditions to inequalities by social class categor
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br Funding This research was funded by the Ministerio
2018-10-24
Funding This research was funded by the Ministerio de Economía y Competitividad, project ref. ECO2013-44027-P. Introduction and objectives The market of food and agriculture products and fish products is immersed in a globalisation process and in a more and more competitive environment, with
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Gmelina arborea is a fast growing tree
2018-10-24
Gmelina arborea is a fast growing tree, which grows on different localities and prefers moist fertile valleys, they attain moderate to large height up to 40 m and 140 cm in diameter (Tewari, 1995). It is occurring naturally throughout greater part of India at altitudes up to 1500 m. It also occurs n
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Terra is one of the
2018-10-23
Terra (2003) is one of the main references in the Brazilian literature. More recently, we can cite the work of Aldrighi and Bisinha (2010). The general conclusion of these authors is that Brazilian firms are indeed credit-constrained. However, at odds with the conventional literature, firms that sho
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However to date all clinical
2018-10-23
However, to date, all clinical trials designed to low levels of Aβ by either blocking activity of β or γ secretases, preventing Aβ aggregation, or promoting Aβ clearance by immunotherapy have failed (Cummings et al., 2014) emphasizing an urgent need to find new therapies for AD. One of the emerging
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the original source The original premise of this
2018-10-23
The original premise of this study was that the melanoma-enriched miRNAs identified in our previous study (Stark et al., 2015) would be translated directly to the expression observed in melanoma patient-derived serum. Evidence for this notion is apparent in the serially collected stage IV melanoma p
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The study by Kl ppel and colleagues
2018-10-23
The study by Klöppel and colleagues can decisively shape future functional neuroimaging research in HD and other neurodegenerative conditions, but we believe that there is much more to learn from this study. The rationale and design should also motivate psychiatric research, where there is still an
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Secondly the pyrazinamide concentrations were approximately
2018-10-23
Secondly, the pyrazinamide concentrations were approximately similar to those in plasma. However, this is substantially lower than the concentrations associated with effective microbial kill at the site of infection. In pulmonary epithelial lining fluid, pyrazinamide is concentrated 17–22-fold, comp
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In acute cases of E coli diarrhea
2018-10-23
In acute cases of E. coli diarrhea, the barrier function of the gut mucosa in the small intestine is compromised. When the pathogen is lysed by phage, in vivo released endotoxins and enterotoxins can thus potentially cross into the circulation. However, no systemic reaction to endotoxin was observed
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Certainly the jury is still out on
2018-10-23
Certainly the jury is still out on the best way to deliver OVs and arguments can be made for either loco-regional or systemic administration. Indeed the flexibility around delivering OVs by different routes, depending on the clinical setting, may be an advantage over more traditional therapeutic mod
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Tenofovir alafenamide TAF National Center
2018-10-23
Tenofovir alafenamide (TAF) (National Center for Biotechnology Information, n.d.-b, CID=9,574,768) is a prodrug of TFV that is more stable in plasma, allowing for a ten-fold reduction in dose and resulting in a 91% reduction in azd2171 TFV while achieving a four-fold increase in intracellular level
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It is unknown how rs SNP located in intron
2018-10-23
It is unknown how rs9838915 SNP located in intron 2 influences LV mass. KLF15 is expressed in cardiomyocytes and acts as a repressor of pathological cardiac hypertrophy (Wang et al., 2008; Fisch et al., 2007; Haldar et al., 2010; Leenders et al., 2012) through inhibition of the cardiac transcription
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In contrast with hydrophilic metabolites
2018-10-23
In contrast with hydrophilic metabolites, the lipid profile was relatively uniform among samples and did not highlight their heterogeneity. The levels CEs with long-chain highly desaturated fatty acids were elevated in tumors; this was consistent with the notion that clear cell RCCs are rich in CEs
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Genome wide association studies GWAS for longevity
2018-10-23
Genome-wide association studies (GWAS) for longevity and healthy aging have only recently moved to the fore in gerontology research. The first consistent association with longevity emerging from GWAS is APOE (Schachter et al., 1994), a gene that has established links to Alzheimer\'s disease (Beecham
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Our data indicated that CRP may be associated
2018-10-23
Our data indicated that CRP may be associated with tissue lesions. In addition to hepatic synthesis (Pfafflin and Schleicher, 2009), CRP can be synthesized by lung EMD638683 cost (e.g. epithelial cells, lymphocytes) (Ramage et al., 2004; Marc et al., 2004). However, local production in extrahepatic
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