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br Conclusions br Study limitations br Conflict of interest
2019-06-11
Conclusions Study limitations Conflict of interest Introduction Dabigatran etexilate, an orally administered pro-drug, is rapidly converted by a serum esterase to dabigatran, a potent, direct, and competitive inhibitor of thrombin. It has an absolute bioavailability of 6.5% and a serum t
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Teniendo en cuenta la labor de
2019-06-11
Teniendo en cuenta la labor de traducción cultural que estos letrados criollos inician en Europa y que piensan como puente de transformaciones culturales y políticas para el espacio americano, analizaremos la traducción que realizan Rodríguez y Mier de la novela Atala de Chateaubriand en el año de 1
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La fotograf a de Mauro Calanchina se imprimi en
2019-06-11
La fotografía de Mauro Calanchina se imprimió en la portada y será éste el momento en el que se inician las modificaciones notch signaling pathway la imagen. El propio Calanchina editó la fotografía, la recortó, limitándose a presentar el ceño del joven que iza un clavel y varios brazos levantados q
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The insulation defect has resulted in dramatic
2019-06-11
The insulation defect has resulted in dramatic “inside-out” extrusion of the inner cables, [2–5] observed in up to 33% of patients in one series, [6] and electrical failure in other leads with normal fluoroscopic appearance. Parvathaneni et al. also observed that of those leads with cable extrusion,
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br Conclusion Accumulating clinical data suggest
2019-06-11
Conclusion Accumulating clinical data suggest the presence of a genetic component in the pathogenesis of AF. In addition to the gene mutations identified in familial AF, the candidate gene approach and GWAS identified genetic risks in the non-familial form of AF. In multiple Western populations,
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Univariate analysis for overall survival revealed that
2019-06-11
Univariate analysis for overall survival revealed that age (≤, >50 years), menopausal status, T-N stage, and histological tumor size were statistically significant factors for survival. Menopausal status was determined after two years of amenorrhea. In post-menopausal women, the disease-free surviva
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A preserva o da ideia de fam lia
2019-06-10
A preservação da ideia de família tradicional tornou-se uma das principais demandas desses representantes. Neste sentido, o Projeto de Lei n° 6583 de 2011, conhecido como Estatuto da Família, almeja o reconhecimento (pelo Estado) da família como uma entidade formada apenas por um homem, uma mulher e
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The combination therapy was exceedingly well
2019-06-10
The combination therapy was exceedingly well tolerated without any side effects to either drug. Remarkably, despite an advanced PV-stage the JAK2V617F allele burden was rapidly lowered from 90% mutated mao inhibitors list at referral to 59% at 6 months, 28% at 10 months and 12% at 16 months of thera
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African leaders are gathering in Addis
2019-06-10
African leaders are gathering in Addis Ababa, Ethiopia, this week for the first ever . The event brings together government officials, including minsters of finance, technical experts, and policymakers, with the goal of advancing the coverage of life-saving immunisations across the continent. In
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An imperative need now exists for new thinking
2019-06-10
An imperative need now exists for new thinking, increased resources, and better training of health-care staff working with these new populations. At a time when there is a danger of religiopolitical extremism in the wake of perceived (and sometimes real) antipathy to newcomers, the health sector has
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WHO estimates that of people with tuberculosis are untreated
2019-06-10
WHO estimates that 30–50% of people with tuberculosis are untreated, in part because of underdiagnosis. Patients with undiagnosed (or diagnosed and untreated) tuberculosis are most likely to transmit infection, so strategies to reduce disease burden should focus on improving the pathway to care for
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All patients with symptomatic cardiac AL amyloidosis had
2019-06-10
All 4 patients with symptomatic cardiac AL amyloidosis had poor prognoses. The median survival period for these 4 patients was 12.3 months (minimum=4 months, maximum=28 months) (Table 1). The patient in Case 2, whose BNP level was the highest of the 4 patients, had the shortest survival period. Howe
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br Discussion SIS is a morphological
2019-06-10
Discussion SIS is a morphological characteristic of the basal interventricular septum that protrudes into the LV cavity. This cardiac malformation has generally been considered a natural part of aging without pathophysiological or clinical significance [5,6]. However, several studies demonstrated
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No final dos anos o apra j estava
2019-06-10
No final dos anos 1960 o apra já estava desalojado da liderança do movimento estudantil, e na década seguinte o apelo guerrilheiro daria lugar conotoxin cost uma atuação colada aos movimentos camponeses, embora a revolução permanecesse no horizonte político desta esquerda, que se propõe a fundar uma
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On what might an argument for a fairer distribution
2019-06-10
On what might an argument for a fairer distribution of malaria research investment rest? The investments analysed by Head and colleagues were those made from outside of sub-Saharan Africa, not by African countries themselves, and were a mix of public funds channelled through bilateral and multilater
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