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Adolescence is a critical period of neural
2018-11-07
Adolescence is a critical period of neural maturation, during which there is reorganization of cortical connections, an increase in the fidelity of corticolimbic interactions, and neurochemical changes that promote adaptive behavioral regulation (). Gray matter develops along a nonlinear trajectory
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br Neural inferences One area where precision is of
2018-11-07
Neural inferences One area where precision is of concern across the cognitive neurosciences is in the specificity of our neural inferences. As we previously suggested (Pfeifer and Allen, 2012), and as nicely summarized by Casey (2015) when considering several models related to dual-systems: “new
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Critical periods are developmental windows in which circuits
2018-11-07
Critical periods are developmental windows in which circuits are more plastic and may be sculpted by the environment or experience (Hensch, 2005). A circuit or brain region might be considered mature when greater stability is achieved after a period of experience-dependent sculpting during an earlie
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However previous cross sectional structural MRI studies expl
2018-11-07
However, previous cross-sectional structural MRI studies exploring the neurobiology of RRBs are limited in ASD. Sears et al. (1999) found a significant negative association between caudate nucleus volume and three Autism Diagnostic Interview (ADI) repetitive behavior items: difficulties with minor
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A recent framework for conceptualizing ELS posits that adver
2018-11-07
A recent framework for conceptualizing ELS posits that adverse early experiences fall along dimensions of threat and deprivation (McLaughlin et al., 2014; Sheridan and McLaughlin, 2014). Here, threat is conceptualized as an atypical experience posing a direct physical danger to a developing order AM
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Despite the limitations this is the first study to
2018-11-07
Despite the limitations, this is the first study to our knowledge to document differences in the associations between GSK343 function and visuospatial memory performance in healthy young adults as a function of childhood income levels. We used prospective data collection over the course of a longitu
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Our results suggest that interindividual differences
2018-11-07
Our results suggest that interindividual differences in neural mirroring are related to successful cooperation. Yet, the causal direction underlying this relation remains an open question. Better interpersonal coordination likely is the result of higher general levels of neural mirroring. Previous r
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NHS Biotin Particularly relevant for mood disorders recent w
2018-11-07
Particularly relevant for mood disorders, recent work has shown that the neuromodulator, dopamine, decreases visually-evoked BOLD signals at the same time as increasing the local cerebral blood flow, suggesting a disproportionate increase in energy metabolism (Zaldivar et al., 2014). Thus, as neurom
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br Urban context The building of Rome s
2018-11-06
Urban context The building of Rome׳s university campus, between 1930 and 1935, represented a complicated and problematic process that xanthine oxidase was deeply intertwined with Italian history. Many cultural transformations took place at that time, particularly in the architectural profession,
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From the data here midline
2018-11-06
From the data here, midline-crossing tumor (p=0.0208) and THZ2 floor invasion (p=0.0196) are significantly related to the presence of cN2c and pN2c. This is consistent with other studies. All pN2c patients were histopathologic and had clinically advanced tumor stage (≥T3), which shows statistically
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The anti inflammatory action has been attributed to polyphen
2018-11-06
The anti-inflammatory action has been attributed to polyphenolic components such as tannins [8] and procyanidins [17] from a variety of natural products. Based on the linkage between the successive monomeric units, procyanidins are classified as Types A, B or C procyanidine polyphenols. Type-A procy
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br Materials and methods br Results and discussion The dose
2018-11-06
Materials and methods Results and discussion The dose-dependent inhibition of HMG-CoA reductase activity by the extracts as presented in Fig. 1 and the IC50 values in Table 1 showed that there was no significant (P>0.05) difference in the inhibitory abilities of the two extracts. The control o
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br Conclusion and future prospects The research on M oleifer
2018-11-06
Conclusion and future prospects The research on M. oleifera is yet to gain importance in India. It is essential that the nutrients of this wonder tree are exploited for a variety of purposes. M. oleifera has great anti-diabetic and anti-cancer properties. However, double blind researches are less
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br Conclusions and future directions
2018-11-06
Conclusions and future directions The toxic effects of Aβ1–42 on hippocampal neurons in culture were reversed by d-β-hydroxybutyrate, suggesting that ketone bodies may have neuroprotective efficacy [53]. Some animal studies have shown that high-fat diets are associated with elevated Aβ loads [78,
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br Methods br Results br Conclusion br Author
2018-11-06
Methods Results Conclusion Author contributions The following are the supplementary data related to this article. Acknowledgments Stemformatics is funded by a grant from the Australian Research Council Special Initiative in Stem Cell Science to CAW through Stem Cells Australia. Stemf
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