• br Conflict of Interest Statement br

  2018-11-03

  

  Conflict of Interest Statement Author Contributions N.M., K.N., M.G., R.J.O., and M.K. performed in vitro and in vivo experiments; N.M., H.D., and M.K., performed protein purification, crystallization, data collection, structure determination, and structural analyses; P.C., and J.D.H. carried

• br Value of the data

  2018-11-03

  

  Value of the data Data This dataset collates the comprehensive proteomic data generated through a SILAC-based quantitative MS approach upon silencing the 65 tyrosine kinases expressed in MCF7 breast cancer AVE 0991 [1]. In addition to the raw data files deposited in the Pride database [2,3],

• br Methods br Results br Discussion br

  2018-11-03

  

  Methods Results Discussion Introduction The use of institutional care for abandoned or orphaned infants and children has remained a common practice throughout the world (Browne et al., 2006; UNICEF, 2015); however, institutional environments are harmful for healthy physical and psycholog

• br A potential adaptive role of dopaminergic reactivity in

  2018-11-03

  

  A potential adaptive role of dopaminergic reactivity in adolescence The view that peaks in DA activity during adolescence underlie increases in risk taking and adolescent psychopathology suggests that adolescents are predisposed toward mental health problems due to hard-wired developmental const

• One explanation for the range of findings observed in the

  2018-11-03

  

  One explanation for the range of findings observed in the current study is that there may be a developmental delay in the formation of the cortical–cortical and corticospinal motor networks in TS. As noted above, motor threshold is thought to depend upon the recruitment of a coherent population of c

• Yet in spite of the increasing number of

  2018-11-03

  

  Yet, in spite of the increasing number of publications on adults, the neurocognitive mechanisms underlying TO in children are less clear. In a recent study, Johnson and collaborators (Johnson et al., 2015) employed a combined spatio-temporal cueing paradigm and found behavioural evidence that 6–16-y

• In surveying the literature support for attention biases tow

  2018-11-03

  

  In surveying the literature, support for attention biases towards appetitive cues appears in the substance abuse and obesity literatures. For example, attention bias towards drug-related cues has been found among alcohol (Field et al., 2004), tobacco (Bradley et al., 2003; Mogg et al., 2005), caffei

• Taken together studies of both neuroanatomy

  2018-11-03

  

  Taken together, studies of both neuroanatomy and neural functional activation yield SES-related differences in sglt regions that support language; these findings, however, have not reliably been linked to differences in language functioning. Importantly, a recent study has shown no measurable diffe

• Emotion regulation is defined as modulating the valence inte

  2018-11-03

  

  Emotion regulation is defined as modulating the valence, intensity, or time-course of an emotional experience (Thompson, 1994). These emotional experiences can range across basic and complex emotions, but, in early childhood, the regulation of anger and frustration is particularly salient as childre

• Despite the fact that all adolescents

  2018-11-03

  

  Despite the fact that all adolescents undergo development of these social and neural systems, engagement in risky behavior varies, with some far more likely than others to partake (Bjork and Pardini, 2015). One likely factor underlying individual differences in risk-taking behavior is function in so

• One clear limitation to the present study is

  2018-11-03

  

  One clear limitation to the present study is the sample size. As a result, while conventional thresholds and covariates were used in statistical models to correct for Type I error, there remains a chance for Type II error, or the chance that analyses were underpowered to detect smaller but meaningfu

• In treatment refractory cases it is also noteworthy

  2018-11-03

  

  In treatment-refractory cases, it is also noteworthy to consider a positron emission tomography (PET) scan to exclude underlying malignant diseases, as illustrated in the case reported by Haroon et al. The patient’s muscle weakness and edema were resistant to corticosteroids, azathioprine, and mycop

• Steel is globally accepted as primarily used material for

  2018-11-03

  

  Steel is globally accepted as primarily used material for the construction of military and non-military vehicles. It is attributed to the features associated with steel, such as high energy absorbing properties, high strength, greater notch toughness and high hardness [1–3]. Selection of suitable ar

• br Influence of target hypersonic movement on radar

  2018-11-03

  

  Influence of target hypersonic movement on radar measurements Since the LFM signal is one of the most famous radar signals, which is of large time-bandwidth product, and can significantly improve S/N ratio when the matching filter is performed. The PC (pulse compression) radar which emits LFM sig

• Desde la aparici n en

  2018-11-03

  

  Desde la aparición en escena de la isna, han comenzado a aparecer otros grupos con una postura de mayor resistencia frente al sistema médico. En 1995, una madre que rechazó la presión médica para la asignación como mujer de su bebé intersexual creó la Ambiguous Genitalia Support Network, que hace qu

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