• br Long term maintenance of hPSCs in a scalable

  2018-11-02

  

  Long term maintenance of hPSCs in a scalable and defined suspension culture system A report published recently in Stem Cell Research (Chen et al., 2012, 8:388–402) extends from these previous studies to demonstrate for the first time, the long term expansion of hESCs retaining the characteristic

• Fibroblasts can be directly reprogrammed into neurons Vierbu

  2018-11-02

  

  Fibroblasts can be directly reprogrammed into neurons (Vierbuchen et al., 2010), cardiomyocytes (Ieda et al., 2010), and NSCs (Han et al., 2012) using tissue-specific combinations of transcription factors. However, the pluripotent reprogramming cocktail of Oct4, Sox2, Klf4, and Myc can also convert

• calcium channel blocker Here using several murine and human

  2018-11-02

  

  Here using several murine and human cellular models, we present compelling evidence for ASYN expression during oligodendrocyte lineage cell development. Moreover, we identified both ASYN protein and transcripts in purified PDGFRA/CD140a+ oligodendrocyte progenitors and oligodendrocyte lineage SOX10+

• In this article we searched

  2018-11-02

  

  In this article, we searched for genes that are induced by KLF4 in a dose-dependent manner and identified Tcl1 as its direct target. KLF4 induces Tcl1 transcription during reprogramming via direct binding to its enhancer and promoter regions, concurrently changing repressive histone marks into activ

• Functional analysis has shown that miR p promotes the differ

  2018-11-02

  

  Functional analysis has shown that miR-342-5p promotes the differentiation of NSCs into INPs. Upregulation of miR-342-5p in cultured NS/PCs in vitro leads to reduced neurosphere formation and colony formation in the floating culture system and adherent culture system, respectively. Clonal analysis i

• To inspect the motion of a particle in bent crystals

  2018-11-02

  

  To inspect the motion of a particle in bent crystals, the old coordinates of the points (x, y, z) in the simulated boxes are transformed into new (x′, y′, z′) by the following rule: where the parameter defines the shape of a bent crystal. The latter equation holds for a bending radius that suffic

• Therefore an increase in the binding energy of hydrogen

  2018-11-02

  

  Therefore, an increase in the binding nae inhibitor of hydrogen is accompanied by the binding energy inside the crystalline lattice decreasing by the same amount, which is associated with a degradation of its mechanical properties [30]. Consequently, the hydrogen-containing material may be assumed

• Note that the values of the

  2018-11-02

  

  Note that the values of the static displacements of lead ions for pure PFW that we obtained are in good agreement with those published in [10]. Conclusion The structural studies that we carried out have established that the distortions of the lineshape of elastic reflections with the Miller indi

• In relation to these twins the structure

  2018-11-02

  

  In relation to these twins the structure defects also perform the opposite function, acting as a stopper. When meeting an impassable stopper, the twinning dislocations halt and the detwinning process comes to an end. The fact that the amount of twins decreases with the load increase (see Fig. 6b) in

• Table shows the results of two level

  2018-11-02

  

  Table 2 shows the results of two-level regression models for urban elders. Model 1 shows that GSK503 ADL limitations and chronic conditions were significantly and positively correlated with depressive symptoms among older adults in urban neighborhoods. The associations between leisure amenities and

• c-Myc tag Nonetheless the analyses presented here have two s

  2018-11-02

  

  Nonetheless, the analyses presented here have two serious limitations. First, we provide no insight into why the imprisonment–mortality association is different for Hispanic females than for other groups (although we do hypothesize briefly above). Second, and as has long been documented in critiques

• Despite intense scrutiny of the harms from smoking we are

  2018-11-02

  

  Despite intense scrutiny of the harms from smoking, we are not aware of a prior study that has investigated, using data at the individual level, whether the risks of death from smoking differ across countries. We believe that such comparisons are best assessed on an additive or risk difference scale

• The etiology was considered idiopathic in all

  2018-11-02

  

  The etiology was considered idiopathic in all cases, based on the high number of complementary exams performed. In the 6 cases in whom the anti-streptolysin-O levels was obtained, only one demonstrated a mildly high level, which does not support the hypothesis of streptococcal infection as a main tr

• br Materials and methods br Results br Discussion

  2018-11-01

  

  Materials and methods Results Discussion This study revealed the optimal conditions required to investigate in vitro epithelial barrier formation using Calu-3 cells, to be used as a screening model for ENM exposure to mimic in vivo conditions. Details on the specific cell line, cell number,

• Jalisco se encuentra entre los estados con mayores niveles e

  2018-11-01

  

  Jalisco se encuentra entre los estados con mayores niveles educativos, de formación profesional y empleo de trabajadores del conocimiento, en tecnologías de la información y la comunicación en el país. En la ocupación de especialistas formados en carreras relacionadas con ingeniería en computación e

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